Skin lesions on the male genital area are a common cause for concern and visits to doctors. The appearance of pimples, papules, spots or sores on the penis can have many different causes - from completely harmless to potentially serious. It is worth knowing what to look out for and how to recognise worrying symptoms and when to consult a specialist. In this article, we present the most common causes of penile lesions, alarm symptoms and the diagnostic pathway.