Alienation of people with schizophrenia can also be related to psychotic states, during which people behave strangely and expose themselves to suspicion from others. This moment can be memorable for a long time for the person with the illness, who imagines that they are compromised.

On the subject of isolation in schizophrenia and depression, Ken Steel's book The Day the Voices Went Silent is worth mentioning. The protagonist here is the author himself describing his struggle with schizophrenia. It caused him to withdraw completely from society and he almost committed suicide because of the voices that accompanied him. His auditory delusions prompted him to jump from a skyscraper, making him think that everyone was suffering because of him. For every tragic event in the world, the author took full responsibility. However, taking medication and participating in psychotherapy silenced his voices and allowed him to return to a normal life.

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There is almost always a risk of suicide in paranoid schizophrenia. Patients become socially marginalised - they lose their jobs, friends and contact with other people. The treatment of schizophrenia includes pharmacotherapy, psychotherapy and sociotherapy. The main principle is to keep the patient in their environment for as long as possible. The premise of modern psychiatry is the principle that the patient should be able to attend therapy meetings so that he or she can return to normal functioning as soon as possible.

Psychotherapy, sociotherapy are parts of the treatment process, especially in the maintenance treatment phase. In the acute phase of the illness, hospitalisation is often necessary. Taking anti-psychotic medication, being active rather than withdrawn or isolated gives a really good chance of returning to society.